Ischaemic stroke: a thrombo-inflammatory disease?
نویسندگان
چکیده
منابع مشابه
Inflammatory markers for ischaemic stroke.
Thromb Haemost 2009; 101: 800–801 Experimental and clinical evidence accumulated since 1990 have established inflammatory processes as important contributors to atherogenesis (1). Based upon this evidence, protein markers of inflammation have been studied as non-invasive indicators of underlying atherosclerosis in apparently healthy individuals and of the risk of cardiovascular events in patien...
متن کاملO10: Thrombo-Inflammation in Acute Ischemic Stroke
Ischemic stroke has been classified as a merely thrombotic disease, so the main goal of its treatment is the recanalization of the occluded vasculature. However, despite fast restoration of blood circulation, progressive stroke still develops in many patients, which has led to the concept of reperfusion injury. The underlying mechanism is only partly known. Though, it is accepted now, tha...
متن کاملAdipose tissue-derived PAI-1: a molecular link for thrombo-inflammatory disease states?
Adipose tissue (particularly the visceral adipose tissue of the omentum) was long thought to be a passive, fat-storing cell clump; however, many years ago this view became out-dated. Numerous studies made us aware of the actual character of this contour-determining part of our body: Adipose tissue is considered to be a true organ capable of producing multiple types of hormones, proand anti-infl...
متن کاملPosterior circulation ischaemic stroke.
There are important differences between posterior and anterior circulation stroke. The differences include the value of screening instruments, optimum diagnos‐ tic modalities, and clinical features (table). The face arm speech test (FAST), a widely used prehospital stroke recognition screening instrument, is less sensitive for detecting posterior circulation stroke than for anterior cir‐ culati...
متن کاملGenetics of ischaemic stroke.
Recent advances in genomics and statistical computation have allowed us to begin addressing the genetic basis of stroke at a molecular level. These advances are at the cusp of making important changes to clinical practice of some monogenic forms of stroke and, in the future, are likely to revolutionise the care provided to these patients. In this review we summarise the state of knowledge in is...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: The Journal of Physiology
سال: 2011
ISSN: 0022-3751
DOI: 10.1113/jphysiol.2011.212886